STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pip5k1cPhosphatidylinositol-4-phosphate 5-kinase, type I, gamma a. (722 aa)    
Predicted Functional Partners:
LOC101173218
Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b.
     
0.935
LOC101169535
Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a.
     
0.935
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
     
0.935
synj1
Synaptojanin 1.
    
 0.935
inpp5e
Inositol polyphosphate-5-phosphatase E.
     
 0.932
LOC101167819
SAC1 like phosphatidylinositide phosphatase b.
    
 0.925
LOC101170855
SAC1 like phosphatidylinositide phosphatase a.
    
 0.925
inpp5f
Inositol polyphosphate-5-phosphatase F.
     
 0.923
LOC101161334
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
     
  0.913
pten
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.912
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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