STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbc1d5TBC1 domain family, member 5. (863 aa)    
Predicted Functional Partners:
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.955
vps26a
VPS26, retromer complex component A.
   
 
 0.918
vps26b
VPS26, retromer complex component B.
   
 
 0.904
pex3
Peroxisomal biogenesis factor 3.
      
 0.671
fkbp15
Peptidylprolyl isomerase.
   
  
 0.597
naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit.
      
 0.560
rab6b
Uncharacterized protein.
   
 
 0.548
RAB41
Uncharacterized protein.
   
 
 0.548
LOC101156359
RAB6B, member RAS oncogene family.
   
 
 0.548
rab6a
RAB6A, member RAS oncogene family.
   
 
 0.548
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (28%) [HD]