STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSORLP00000039022Plectin b. (5545 aa)    
Predicted Functional Partners:
itgb4
Integrin beta.
  
 0.744
LOC101173369
Junction plakoglobin a.
   
 0.601
LOC101167517
Keratin 97; Belongs to the intermediate filament family.
   
 0.557
LOC101165005
Desmocollin 2 like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.544
LOC101167610
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.
      
 0.517
LOC101173720
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.479
LOC101171502
Uncharacterized protein.
    
 0.476
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.476
LOC101167707
Keratin 5; Belongs to the intermediate filament family.
    
 0.466
perp
P53 apoptosis effector related to pmp22.
   
 
 0.447
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.