STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110014047IRS-type PTB domain-containing protein. (494 aa)    
Predicted Functional Partners:
crk
CRK proto-oncogene, adaptor protein.
    
 0.542
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.542
LOC110016423
Uncharacterized protein.
    
 0.542
LOC101165394
GRB2 related adaptor protein 2a.
    
 0.464
LOC101166194
GRB2 related adaptor protein b.
    
 0.464
LOC101160815
GRB2 related adaptor protein a.
    
 0.464
grb2
Growth factor receptor-bound protein 2b.
    
 0.464
LOC101172160
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.435
ptpn6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.435
ptpn11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.435
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.