STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edaraddEDAR-associated death domain. (216 aa)    
Predicted Functional Partners:
edar
Tumor necrosis factor receptor superfamily member EDAR; Receptor for EDA (By similarity). May mediate the activation of NF-kappa-B and JNK.
    
 0.919
eda
Ectodysplasin A; Belongs to the tumor necrosis factor family.
     
 0.771
pum1
Pumilio RNA-binding family member 1.
   
 
 0.680
pum2
Pumilio 2.
   
 
 0.680
cnot1
CCR4-NOT transcription complex, subunit 1.
    
 
 0.655
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.535
LOC101164086
Actinin, alpha 2b.
      
 0.511
LOC101170323
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.484
hps1
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.
      
 0.463
LOC101155367
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.451
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.