STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101168711Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (475 aa)    
Predicted Functional Partners:
lef1
Lymphoid enhancer-binding factor 1.
    
 0.983
tcf7l1
HMG box domain-containing protein.
    
 0.978
LOC111948314
HMG box domain-containing protein.
    
 0.978
tcf7
Transcription factor 7.
    
 0.978
map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
0.972
foxo3
Forkhead box O5.
    
 0.911
foxo1
Fork-head domain-containing protein.
    
 0.911
LOC110015734
Forkhead box O4.
    
 0.911
LOC101164740
Fork-head domain-containing protein.
    
 0.910
LOC101155614
Forkhead box O6 b.
    
  0.902
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.