STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mark3Non-specific serine/threonine protein kinase. (750 aa)    
Predicted Functional Partners:
ksr1
Kinase suppressor of ras 1a.
    
0.648
acp1
LMWPc domain-containing protein.
      
 0.603
emc10
ER membrane protein complex subunit 10.
      
 0.596
tnip1
TNFAIP3 interacting protein 1.
      
 0.561
ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
      
 0.543
hexb
Beta-hexosaminidase.
      
 0.541
rrbp1
Ribosome binding protein 1a.
     
 0.540
slc31a2
Solute carrier family 31 member 2.
      
 0.536
Dst
EF-hand domain-containing protein.
   
 
 0.535
khsrp
KH-type splicing regulatory protein.
   
  
 0.532
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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