STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbk1TANK-binding kinase 1. (665 aa)    
Predicted Functional Partners:
LOC101158892
Interferon regulatory factor 3.
   
 0.976
tank
TRAF family member-associated NFKB activator.
   
 0.965
sting1
Transmembrane protein 173.
   
 0.954
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.930
traf3
TNF receptor-associated factor.
   
 0.925
optn
Optineurin.
   
 0.906
LOC101170323
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.896
LOC101172593
Tumor necrosis factor a (TNF superfamily, member 2).
   
 0.877
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.866
azi2
5-azacytidine induced 2.
   
 
 0.859
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.