STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf5Interferon regulatory factor 5. (475 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.766
scarb1
Scavenger receptor class B, member 1; Belongs to the CD36 family.
   
  
 0.559
aldh8a1
Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family.
    
 
 0.557
tbk1
TANK-binding kinase 1.
   
 0.547
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.530
tlr3
Toll-like receptor 3.
   
 
 0.513
LOC101163430
Interferon regulatory factor.
  
0.493
sting1
Transmembrane protein 173.
   
 0.472
ripk4
Receptor-interacting serine-threonine kinase 4.
   
 0.471
plk2
Serine/threonine-protein kinase PLK.
   
 0.444
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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