STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptbp1Polypyrimidine tract binding protein 1a. (577 aa)    
Predicted Functional Partners:
hnrnpk
Heterogeneous nuclear ribonucleoprotein K.
   
 0.811
cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
      
 0.677
HNRNPLL
Heterogeneous nuclear ribonucleoprotein L like.
  
0.668
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
 0.663
LOC101166731
Uncharacterized protein.
   
0.650
hnrnpl
Heterogeneous nuclear ribonucleoprotein L.
   
0.650
LOC101167466
Heterogeneous nuclear ribonucleoprotein K, like.
   
 0.632
LOC101165877
RNA binding motif protein 5.
    
 0.602
ENSORLP00000032276
Uncharacterized protein.
    
 0.602
polr2l
Polymerase (RNA) II (DNA directed) polypeptide L.
   
 
  0.571
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.