STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101157159Regulator of G protein signaling 5b. (183 aa)    
Predicted Functional Partners:
GNAZ
G protein subunit alpha z.
   
 0.686
gnb5
Guanine nucleotide binding protein (G protein), beta 5a.
   
 0.666
LOC101156727
Guanine nucleotide binding protein (G protein), beta 5b.
   
 0.666
LOC101158106
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 0.662
LOC101158659
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.
   
 0.662
LOC105358374
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
   
 0.615
LOC101174025
Uncharacterized protein.
   
 0.615
gnao1
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.
   
 0.615
gnai3
Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]
   
 0.615
LOC101155991
Guanine nucleotide binding protein (G protein) alpha v1.
   
 0.615
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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