STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1252 aa)    
Predicted Functional Partners:
kras
GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.
    
 0.957
rasgrf2
Ras protein-specific guanine nucleotide-releasing factor 2b.
  
  
0.946
hras
HRas proto-oncogene, GTPase a.
    
 0.941
mras
Muscle RAS oncogene homolog.
   
 0.941
LOC101154954
Zgc:55558.
    
 0.941
LOC101174431
RAS related.
   
 0.941
rras2
RAS related 2.
   
 0.941
LOC101155194
Uncharacterized protein.
   
 0.936
LOC101173444
Uncharacterized protein.
   
 0.936
LOC101158607
Uncharacterized protein.
   
 0.936
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.