STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
avenApoptosis, caspase activation inhibitor. (326 aa)    
Predicted Functional Partners:
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.983
ENSORLP00000040907
TROVE domain-containing protein.
    
 0.805
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.615
LOC101164440
Cystatin domain-containing protein.
    
 0.594
LOC101165252
Cystatin domain-containing protein; Belongs to the cystatin family.
    
 0.594
tpx2
TPX2 microtubule nucleation factor.
    
 0.594
ENSORLP00000037834
Cystatin domain-containing protein.
    
 0.594
ENSORLP00000041676
Cystatin domain-containing protein.
    
 0.594
LOC101171465
Cystatin domain-containing protein.
    
 0.594
sec63
SEC63 homolog, protein translocation regulator.
      
 0.559
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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