STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSORLP00000042326Dickkopf_N domain-containing protein. (172 aa)    
Predicted Functional Partners:
kremen1
Kringle containing transmembrane protein 1.
    
 0.749
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.574
lrp6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.574
LOC101172518
Dickkopf WNT signaling pathway inhibitor 1a.
     
0.544
LOC101157150
WSC domain containing 1b.
    
 0.462
CENPS
Centromere protein S.
    
 0.462
wscd2
WSC domain containing 2.
    
 0.462
LOC101173302
Cortistatin.
    
 0.462
LOC101164577
Cytochrome c oxidase subunit 7A1.
  
    0.444
cd59
CD59 molecule (CD59 blood group).
   
 0.408
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.