STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101170588Zgc:136971. (757 aa)    
Predicted Functional Partners:
ist1
IST1 factor associated with ESCRT-III.
    
 
 0.542
prep
Prolyl endopeptidase.
   
 
 0.507
ENSORLP00000032656
Uncharacterized protein.
   
 
  0.485
lepa
Leptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot.
     
 0.474
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 
 0.451
Grp
Uncharacterized protein.
   
 
 0.448
NCSTN
Nicastrin.
   
  
 0.431
LOC101164837
Uncharacterized protein.
   
 
  0.418
LOC101159451
Uncharacterized protein.
   
 
  0.418
H2LYX4_ORYLA
Si:dkey-211g8.9.
     
 0.417
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.