STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrwd1Leucine-rich repeats and WD repeat domain containing 1. (742 aa)    
Predicted Functional Partners:
orc2
Origin recognition complex, subunit 2.
    
 0.938
orc3
Origin recognition complex, subunit 3.
    
 0.925
orc5
Origin recognition complex, subunit 5.
   
 0.921
orc4
Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.
    
 0.793
orc1
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.746
ticrr
Treslin_N domain-containing protein.
   
 
 0.612
ENSORLP00000028654
SUEL-type lectin domain-containing protein.
    
   0.590
ENSORLP00000034371
SUEL-type lectin domain-containing protein.
    
   0.590
LOC101172768
Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.
    
   0.590
adgrl2
Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.
    
   0.590
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.