STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
jak1Tyrosine-protein kinase. (1170 aa)    
Predicted Functional Partners:
LOC101173855
Signal transducer and activator of transcription.
   
 0.987
LOC101154761
Signal transducer and activator of transcription.
   
 0.978
socs3
Suppressor of cytokine signaling 3a.
   
 0.971
stat3
Signal transducer and activator of transcription.
   
 0.946
LOC101157629
Tyrosine-protein kinase.
  
  
0.940
LOC101168468
Tyrosine-protein kinase.
  
  
 
0.938
LOC101158490
Signal transducer and activator of transcription.
    
 0.933
ifngr1l
Fibronectin type-III domain-containing protein.
     
 0.928
tyk2
Tyrosine-protein kinase.
  
  
0.926
LOC101162184
Signal transducer and activator of transcription.
   
 0.905
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.