STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ksr1Kinase suppressor of ras 1a. (978 aa)    
Predicted Functional Partners:
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
0.972
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
0.849
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
 0.849
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.849
LOC101160979
Ribosomal protein L10.
    
 
 0.825
ppp5c
Serine/threonine-protein phosphatase.
   
 0.779
ENSORLP00000037708
annotation not available
   
 0.754
araf
A-Raf proto-oncogene, serine/threonine kinase.
    
0.735
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
0.735
brap
BRCA1 associated protein.
    
 0.663
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.