STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC110016899Thrombopoietin. (177 aa)    
Predicted Functional Partners:
mpl
MPL proto-oncogene, thrombopoietin receptor.
    
 0.873
cd34
Uncharacterized protein.
      
 0.686
Kitlg
Kit ligand a.
      
 0.659
zranb2
Zinc finger, RAN-binding domain containing 2.
      
 0.637
epo
Erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family.
      
 0.620
LOC101163579
Erythropoietin receptor.
      
 0.559
rpl32
Ribosomal protein L32.
      
 0.558
LOC100125525
Uncharacterized protein.
      
 0.535
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
      
 0.489
fosb
FBJ murine osteosarcoma viral oncogene homolog B.
      
 0.457
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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