Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSAPOP00000000076Si:dkey-76k16.5. (264 aa)    
Predicted Functional Partners:
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.928
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.894
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 0.752
ccnj
Cyclin J; Belongs to the cyclin family.
   
 0.752
LOC110969425
Cyclin J-like; Belongs to the cyclin family.
   
 0.752
ccnf
Cyclin F; Belongs to the cyclin family.
   
 0.752
ccna1
Cyclin A1; Belongs to the cyclin family.
   
 0.752
LOC110949587
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
   
 
 0.742
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
   
 
 0.742
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 
 0.738
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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