Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110950024Cystatin C (amyloid angiopathy and cerebral hemorrhage); Belongs to the cystatin family. (135 aa)    
Predicted Functional Partners:
ENSAPOP00000031391
Cystatin domain-containing protein.
     
  0.844
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.635
LOC110968736
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.632
ctso
Cathepsin O; Belongs to the peptidase C1 family.
   
 0.632
LOC110951564
Uncharacterized protein.
   
 0.610
LOC110956220
Uncharacterized protein.
   
 0.610
LOC110961314
Granulin b.
   
 0.610
cd74
CD74 molecule, major histocompatibility complex, class II invariant chain a.
   
 0.604
LOC110945757
Cystatin domain-containing protein.
    
 0.604
LOC110945756
Cystatin domain-containing protein; Belongs to the cystatin family.
    
 0.604
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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