Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
p4hbProtein disulfide-isomerase. (513 aa)    
Predicted Functional Partners:
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 0.989
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.976
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.976
pdia4
Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.
   
  0.975
pdia3
Protein disulfide-isomerase.
   
  0.975
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
  
 0.970
txndc5
Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.
   
 0.965
suox
Sulfite oxidase.
   
 0.941
LOC110965385
Calreticulin.
   
 0.933
LOC110957591
Calreticulin 3b.
   
 0.933
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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