Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
suv39h1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)    
Predicted Functional Partners:
sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 0.985
setdb1
SET domain bifurcated histone lysine methyltransferase 1b.
    
 0.972
LOC110970376
SET domain-containing protein.
    
 0.972
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 0.971
ddb1
Damage-specific DNA binding protein 1.
    
 
 0.951
ezh2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
 0.946
dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 0.946
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 0.946
prdm2
PR domain containing 2, with ZNF domain b.
    
 0.942
LOC110955903
PR domain containing 2, with ZNF domain a.
    
 0.942
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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