| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdc45 | cdc6 | ENSAPOP00000033220 | ENSAPOP00000026230 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.972 |
| cdc45 | cdt1 | ENSAPOP00000033220 | ENSAPOP00000020816 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Chromatin licensing and DNA replication factor 1. | 0.987 |
| cdc45 | mcm2 | ENSAPOP00000033220 | ENSAPOP00000028396 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | mcm5 | ENSAPOP00000033220 | ENSAPOP00000022125 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | mcm6 | ENSAPOP00000033220 | ENSAPOP00000026175 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc45 | orc2 | ENSAPOP00000033220 | ENSAPOP00000008091 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex, subunit 2. | 0.990 |
| cdc45 | orc3 | ENSAPOP00000033220 | ENSAPOP00000011016 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex, subunit 3. | 0.997 |
| cdc45 | orc4 | ENSAPOP00000033220 | ENSAPOP00000013580 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.909 |
| cdc45 | orc5 | ENSAPOP00000033220 | ENSAPOP00000001148 | CDC45 cell division cycle 45 homolog (S. cerevisiae). | Origin recognition complex, subunit 5. | 0.996 |
| cdc6 | cdc45 | ENSAPOP00000026230 | ENSAPOP00000033220 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | CDC45 cell division cycle 45 homolog (S. cerevisiae). | 0.972 |
| cdc6 | cdt1 | ENSAPOP00000026230 | ENSAPOP00000020816 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Chromatin licensing and DNA replication factor 1. | 0.999 |
| cdc6 | mcm2 | ENSAPOP00000026230 | ENSAPOP00000028396 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.999 |
| cdc6 | mcm5 | ENSAPOP00000026230 | ENSAPOP00000022125 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.997 |
| cdc6 | mcm6 | ENSAPOP00000026230 | ENSAPOP00000026175 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | DNA helicase; Belongs to the MCM family. | 0.998 |
| cdc6 | orc2 | ENSAPOP00000026230 | ENSAPOP00000008091 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex, subunit 2. | 0.998 |
| cdc6 | orc3 | ENSAPOP00000026230 | ENSAPOP00000011016 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex, subunit 3. | 0.999 |
| cdc6 | orc4 | ENSAPOP00000026230 | ENSAPOP00000013580 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. | 0.999 |
| cdc6 | orc5 | ENSAPOP00000026230 | ENSAPOP00000001148 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | Origin recognition complex, subunit 5. | 0.999 |
| cdt1 | cdc45 | ENSAPOP00000020816 | ENSAPOP00000033220 | Chromatin licensing and DNA replication factor 1. | CDC45 cell division cycle 45 homolog (S. cerevisiae). | 0.987 |
| cdt1 | cdc6 | ENSAPOP00000020816 | ENSAPOP00000026230 | Chromatin licensing and DNA replication factor 1. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |