SFMBT1 protein (Acanthochromis polyacanthus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

SFMBT1

Scm like with four mbt domains 1. (866 aa)

Predicted Functional Partners:

sfmbt2

0.873

kdm1a

0.785

LOC110972201

0.762

rybp

0.762

YAF2

0.762

HMG20A

0.738

LOC110962630

0.738

LOC110945566

0.738

RING1

0.697

rnf2

0.697

Your Current Organism:

Acanthochromis polyacanthus

NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HMG20A	SFMBT1	ENSAPOP00000008410	ENSAPOP00000001180	High mobility group 20A.	Scm like with four mbt domains 1.	0.738
HMG20A	kdm1a	ENSAPOP00000008410	ENSAPOP00000011557	High mobility group 20A.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.957
HMG20A	sfmbt2	ENSAPOP00000008410	ENSAPOP00000014465	High mobility group 20A.	Scm like with four mbt domains 2.	0.738
LOC110945566	SFMBT1	ENSAPOP00000017570	ENSAPOP00000001180	High mobility group 20A.	Scm like with four mbt domains 1.	0.738
LOC110945566	kdm1a	ENSAPOP00000017570	ENSAPOP00000011557	High mobility group 20A.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.957
LOC110945566	sfmbt2	ENSAPOP00000017570	ENSAPOP00000014465	High mobility group 20A.	Scm like with four mbt domains 2.	0.738
LOC110962630	SFMBT1	ENSAPOP00000011852	ENSAPOP00000001180	High mobility group protein 20A-like.	Scm like with four mbt domains 1.	0.738
LOC110962630	kdm1a	ENSAPOP00000011852	ENSAPOP00000011557	High mobility group protein 20A-like.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.957
LOC110962630	sfmbt2	ENSAPOP00000011852	ENSAPOP00000014465	High mobility group protein 20A-like.	Scm like with four mbt domains 2.	0.738
LOC110972201	RING1	ENSAPOP00000010242	ENSAPOP00000001617	YY1 associated factor 2.	Ring finger protein 1.	0.951
LOC110972201	SFMBT1	ENSAPOP00000010242	ENSAPOP00000001180	YY1 associated factor 2.	Scm like with four mbt domains 1.	0.762
LOC110972201	YAF2	ENSAPOP00000010242	ENSAPOP00000014149	YY1 associated factor 2.	YY1 associated factor 2.	0.865
LOC110972201	rnf2	ENSAPOP00000010242	ENSAPOP00000007845	YY1 associated factor 2.	Ring finger protein 2.	0.951
LOC110972201	rybp	ENSAPOP00000010242	ENSAPOP00000011743	YY1 associated factor 2.	RING1 and YY1 binding protein b.	0.824
LOC110972201	sfmbt2	ENSAPOP00000010242	ENSAPOP00000014465	YY1 associated factor 2.	Scm like with four mbt domains 2.	0.762
RING1	LOC110972201	ENSAPOP00000001617	ENSAPOP00000010242	Ring finger protein 1.	YY1 associated factor 2.	0.951
RING1	SFMBT1	ENSAPOP00000001617	ENSAPOP00000001180	Ring finger protein 1.	Scm like with four mbt domains 1.	0.697
RING1	YAF2	ENSAPOP00000001617	ENSAPOP00000014149	Ring finger protein 1.	YY1 associated factor 2.	0.951
RING1	kdm1a	ENSAPOP00000001617	ENSAPOP00000011557	Ring finger protein 1.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.843
RING1	rnf2	ENSAPOP00000001617	ENSAPOP00000007845	Ring finger protein 1.	Ring finger protein 2.	0.936