Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110957597Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1136 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.937
LOC110961776
Transmembrane phosphatase with tensin homology.
    
 0.863
LOC110945409
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.863
ENSAPOP00000034206
Phosphatase tensin-type domain-containing protein.
    
 0.863
igsf5
Immunoglobulin superfamily, member 5a.
   
 0.824
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6.
    
 0.822
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
    
 0.822
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16.
    
   0.762
grasp
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein.
    
 0.762
ARHGEF26
Rho guanine nucleotide exchange factor 26.
    
   0.747
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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