Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MACROD2Macro domain-containing protein. (411 aa)    
Predicted Functional Partners:
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.851
xpc
Xeroderma pigmentosum, complementation group C.
    
   0.764
akt1s1
AKT1 substrate 1 (proline-rich).
   
    0.708
gdap2
Ganglioside induced differentiation associated protein 2.
  
   
0.704
adprhl2
ADP-ribosylhydrolase like 2.
    
 
 0.688
tep1
Uncharacterized protein.
    
 
 0.687
parp2
Poly [ADP-ribose] polymerase.
    
 
 0.685
oard1
O-acyl-ADP-ribose deacylase 1.
    
 
 0.636
aifm1
Apoptosis inducing factor mitochondrion associated 1.
  
 0.621
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit.
    
   0.605
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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