Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC110955279Cylindromatosis (turban tumor syndrome), b. (708 aa)    
Predicted Functional Partners:
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.989
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.982
sqstm1
Sequestosome 1.
    
 0.974
LOC110965726
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.970
ikbke
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.963
tbk1
TANK-binding kinase 1.
    
 0.944
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.931
LOC110971125
Uncharacterized protein.
    
 0.923
rnf31
Uncharacterized protein.
    
 0.923
bcl3
BCL3 transcription coactivator.
   
 0.922
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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