STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
npc2Niemann-Pick disease, type C2. (164 aa)    
Predicted Functional Partners:
npc1
Niemann-Pick disease, type C1.
   
 0.994
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.989
ENSAPOP00000015128
Uncharacterized protein.
   
 0.955
scap
SREBF chaperone.
   
 0.955
smpdl3a
Acid sphingomyelinase-like phosphodiesterase.
   
 
  0.712
ptchd4
Patched domain containing 4.
   
 
  0.711
PTCHD3
Patched domain containing 3.
   
 
  0.711
plekhd1
Pleckstrin homology domain containing, family D (with coiled-coil domains) member 1.
   
 
  0.711
PTCHD3-2
Patched domain containing 3.
   
 
  0.711
ptchd1
Patched domain containing 1.
   
 
  0.711
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.