Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC110971568TIR domain-containing protein; Belongs to the Toll-like receptor family. (950 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.790
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.681
ENSAPOP00000024610
Uncharacterized protein.
    
  0.617
ENSAPOP00000028898
Uncharacterized protein.
    
  0.617
LOC110953045
Transmembrane p24 trafficking protein 7.
    
 0.587
ENSAPOP00000033084
Transmembrane p24 trafficking protein 3.
    
 0.587
LOC110956530
TRIF-NTD domain-containing protein.
    
 0.587
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
    
 0.554
hspa9
Heat shock protein 9; Belongs to the heat shock protein 70 family.
    
  0.532
LOC110964456
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
  0.532
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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