Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccna2Cyclin A2; Belongs to the cyclin family. (436 aa)    
Predicted Functional Partners:
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.996
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.994
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.994
e2f1
E2F transcription factor 1.
   
 0.991
cdt1
Chromatin licensing and DNA replication factor 1.
   
 0.988
cdc20b
Uncharacterized protein.
   
 0.988
cdc20
Cell division cycle 20 homolog.
   
 0.988
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 0.986
LOC110961378
WD_REPEATS_REGION domain-containing protein.
   
 0.986
LOC110950752
Fizzy/cell division cycle 20 related 1b.
   
 0.986
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.