Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
igf1Insulin-like growth factor 1. (158 aa)    
Predicted Functional Partners:
igf1r
Tyrosine-protein kinase receptor.
   
 
 0.916
LOC110961142
Tyrosine-protein kinase receptor.
   
 
 0.916
ENSAPOP00000026642
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.902
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.902
IGFBP3
Insulin like growth factor binding protein 3.
     
 0.876
LOC110955659
Insulin-like growth factor binding protein 3.
     
 0.876
insr
Tyrosine-protein kinase receptor.
   
 
 0.874
ENSAPOP00000014640
Tyrosine-protein kinase receptor.
   
 
 0.874
LOC110967773
Uncharacterized protein.
   
 
 0.874
LOC110951820
Fibroblast growth factor receptor 4.
     
  0.873
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (10%) [HD]