STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddx1DEAD (Asp-Glu-Ala-Asp) box helicase 1. (740 aa)    
Predicted Functional Partners:
rtcb
RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
   
 0.990
rtraf
RNA transcription, translation and transport factor.
   
 0.989
fam98b
Family with sequence similarity 98 member B.
    
 0.976
fam98a
Uncharacterized protein.
   
 
 0.967
cunh2orf49
Si:dkeyp-118h3.6.
    
 0.952
LOC110963267
Uncharacterized protein.
   
 
 0.924
psmc1
Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.
  
 
 0.851
cops3
COP9 signalosome subunit 3.
   
   0.847
psmc5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
  
 
 0.842
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
   0.815
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.