Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sbno1Strawberry notch homolog 1 (Drosophila). (1165 aa)    
Predicted Functional Partners:
LOC110954260
Uncharacterized protein.
 
      0.891
cdk2ap2
Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family.
     
 0.840
CDK2AP1
Cyclin dependent kinase 2 associated protein 1.
 
   
 0.830
LOC110957650
Interleukin 22 receptor, alpha 2.
      
 0.601
ENSAPOP00000002920
Vestigial-like family member 2a.
    
   0.597
nol8
RRM domain-containing protein.
      
 0.488
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
      
 0.476
sox5
SRY-box transcription factor 5.
      
 0.467
dyrk2
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2.
    
 
 0.455
LOC110953342
Dual specificity tyrosine phosphorylation regulated kinase 3.
    
 
 0.455
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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