Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110958140Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (961 aa)    
Predicted Functional Partners:
mycbp2
MYC binding protein 2.
    
 0.978
map2k7
Mitogen-activated protein kinase kinase 7.
    
 0.938
MAP3K12
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
     
  0.873
map3k13
Mitogen-activated protein kinase kinase kinase.
     
  0.873
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.798
LOC110963776
FRA10A associated CGG repeat 1.
    
   0.559
CDC25B
Cell division cycle 25B.
   
  
 0.523
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.517
mapk8ip2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 
 0.517
fbxo45
F-box protein 45.
    
 
 0.513
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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