Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ndrg3Ndrg family member 3a. (384 aa)    
Predicted Functional Partners:
trpc4ap
Transient receptor potential cation channel, subfamily C, member 4 associated protein a.
      
 0.680
edem2
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
      
 0.596
LOC110962689
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.551
ENSAPOP00000007888
Cardiolipin synthase 1.
     
  0.520
kpna4
Importin subunit alpha; Belongs to the importin alpha family.
      
 0.500
dnajb11
DnaJ heat shock protein family (Hsp40) member B11.
     
 0.500
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta).
    
 0.464
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3.
    
 0.464
hdhd3
Haloacid dehalogenase-like hydrolase domain containing 3.
    
 
 0.462
lclat1
Lysocardiolipin acyltransferase 1.
    
 0.444
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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