STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
git1G protein-coupled receptor kinase interacting ArfGAP 1. (782 aa)    
Predicted Functional Partners:
ENSAPOP00000030863
Intersectin 2a.
   
 
 0.978
LOC110950796
Intersectin 2b.
   
 
 0.978
LOC110953063
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.974
pxn
Uncharacterized protein.
    
 0.974
arhgef7
Rho guanine nucleotide exchange factor (GEF) 7a.
    
 0.973
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
    
 0.973
LOC110964925
Rho guanine nucleotide exchange factor (GEF) 7b.
    
 0.973
LOC110963213
Leupaxin.
    
 0.877
TGFB1I1
Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
    
 0.877
CDC42
Cell division cycle 42.
    
 0.812
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.