Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC110964117Potassium inwardly-rectifying channel, subfamily J, member 1b. (385 aa)    
Predicted Functional Partners:
LOC110969868
Protein kinase domain-containing protein.
     
 0.860
sgk2
Serum/glucocorticoid regulated kinase 2a; Belongs to the protein kinase superfamily.
     
 0.860
LOC110969757
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
 0.860
ENSAPOP00000019762
Potassium inwardly-rectifying channel, subfamily J, member 16.
   
 
  0.748
LOC110962859
Uncharacterized protein.
   
 
  0.748
LOC110960291
Uncharacterized protein.
    
  0.712
LOC110959480
Potassium inwardly-rectifying channel, subfamily J, member 2a.
    
  0.712
LOC110962867
Potassium inwardly-rectifying channel, subfamily J, member 2b.
    
  0.712
LOC110964034
Potassium inwardly-rectifying channel, subfamily J, member 12a.
    
  0.712
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.687
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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