Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110949964Hcy-binding domain-containing protein. (408 aa)    
Predicted Functional Partners:
dmgdh
Dimethylglycine dehydrogenase.
 
 
 0.952
mthfr
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.935
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.928
cth
Cystathionase (cystathionine gamma-lyase), like.
  
 
 0.928
ahcy
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
  
 
 0.924
LOC110970625
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.923
aldh7a1
Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family.
  
 0.910
LOC110952327
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.907
mat2b
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
  
 
 0.906
tat
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
  
 
 0.900
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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