Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110956441Membrane associated guanylate kinase, WW and PDZ domain containing 1a. (1519 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.978
igsf5
Immunoglobulin superfamily, member 5a.
   
 0.959
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6.
    
 0.939
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
    
 0.939
synpo
Uncharacterized protein.
     
 0.903
LOC110953218
Actinin, alpha 1.
    
 0.896
ACTN4
Uncharacterized protein.
    
 0.896
LOC110961776
Transmembrane phosphatase with tensin homology.
    
 0.885
LOC110945409
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.885
ENSAPOP00000034206
Phosphatase tensin-type domain-containing protein.
    
 0.885
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (8%) [HD]