Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110956431Renin; Belongs to the peptidase A1 family. (396 aa)    
Predicted Functional Partners:
ace
Angiotensin-converting enzyme.
     
 0.896
ace2
Angiotensin-converting enzyme.
     
 0.883
agt
Angiotensinogen; Belongs to the serpin family.
    
 0.873
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 0.856
atp6ap2
ATPase H+ transporting accessory protein 2.
   
 0.849
LOC110968736
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.842
LOC110951763
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.831
LOC110950793
Cathepsin Ba; Belongs to the peptidase C1 family.
   
 0.831
LOC110965153
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 0.826
ctso
Cathepsin O; Belongs to the peptidase C1 family.
   
 0.826
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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