Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC110962897Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (388 aa)    
Predicted Functional Partners:
prkar1b
Protein kinase, cAMP-dependent, regulatory, type I, beta.
 
 
 0.989
prkar2a
Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.
   
 0.980
prkar1a
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b.
   
 0.980
LOC110957354
Protein kinase, cAMP-dependent, regulatory, type II, alpha A.
   
 0.980
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.979
prkar2b
Protein kinase cAMP-dependent type II regulatory subunit beta.
   
 0.979
pln
Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
    
 0.963
ENSAPOP00000017627
Uncharacterized protein.
   
 0.957
LOC110955993
Uncharacterized protein.
   
 0.957
lipe
Lipase, hormone-sensitive b.
    
 0.938
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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