CIITA protein (Acanthochromis polyacanthus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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[Homology]

Score

CIITA

Class II major histocompatibility complex transactivator. (990 aa)

Predicted Functional Partners:

rfx5

0.999

rfxank

0.988

LOC110946864

0.988

rfxap

0.973

nfya

0.932

nfyb

0.929

psmc5

0.909

LOC110971610

0.900

stat3

0.900

stat4

0.900

Your Current Organism:

Acanthochromis polyacanthus

NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIITA	LOC110946864	ENSAPOP00000002686	ENSAPOP00000011468	Class II major histocompatibility complex transactivator.	ANK_REP_REGION domain-containing protein.	0.988
CIITA	LOC110971610	ENSAPOP00000002686	ENSAPOP00000000783	Class II major histocompatibility complex transactivator.	Signal transducer and activator of transcription.	0.900
CIITA	nfya	ENSAPOP00000002686	ENSAPOP00000001325	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y, alpha, like.	0.932
CIITA	nfyb	ENSAPOP00000002686	ENSAPOP00000027997	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y, beta a.	0.929
CIITA	psmc5	ENSAPOP00000002686	ENSAPOP00000018264	Class II major histocompatibility complex transactivator.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.909
CIITA	rfx5	ENSAPOP00000002686	ENSAPOP00000012617	Class II major histocompatibility complex transactivator.	Regulatory factor X, 5.	0.999
CIITA	rfxank	ENSAPOP00000002686	ENSAPOP00000002049	Class II major histocompatibility complex transactivator.	Regulatory factor X-associated ankyrin-containing protein.	0.988
CIITA	rfxap	ENSAPOP00000002686	ENSAPOP00000034766	Class II major histocompatibility complex transactivator.	Regulatory factor X-associated protein.	0.973
CIITA	stat3	ENSAPOP00000002686	ENSAPOP00000002542	Class II major histocompatibility complex transactivator.	Signal transducer and activator of transcription.	0.900
CIITA	stat4	ENSAPOP00000002686	ENSAPOP00000012939	Class II major histocompatibility complex transactivator.	Signal transducer and activator of transcription.	0.900
LOC110946864	CIITA	ENSAPOP00000011468	ENSAPOP00000002686	ANK_REP_REGION domain-containing protein.	Class II major histocompatibility complex transactivator.	0.988
LOC110946864	nfya	ENSAPOP00000011468	ENSAPOP00000001325	ANK_REP_REGION domain-containing protein.	Nuclear transcription factor Y, alpha, like.	0.419
LOC110946864	rfx5	ENSAPOP00000011468	ENSAPOP00000012617	ANK_REP_REGION domain-containing protein.	Regulatory factor X, 5.	0.995
LOC110946864	rfxap	ENSAPOP00000011468	ENSAPOP00000034766	ANK_REP_REGION domain-containing protein.	Regulatory factor X-associated protein.	0.995
LOC110971610	CIITA	ENSAPOP00000000783	ENSAPOP00000002686	Signal transducer and activator of transcription.	Class II major histocompatibility complex transactivator.	0.900
LOC110971610	nfya	ENSAPOP00000000783	ENSAPOP00000001325	Signal transducer and activator of transcription.	Nuclear transcription factor Y, alpha, like.	0.546
LOC110971610	stat3	ENSAPOP00000000783	ENSAPOP00000002542	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.657
nfya	CIITA	ENSAPOP00000001325	ENSAPOP00000002686	Nuclear transcription factor Y, alpha, like.	Class II major histocompatibility complex transactivator.	0.932
nfya	LOC110946864	ENSAPOP00000001325	ENSAPOP00000011468	Nuclear transcription factor Y, alpha, like.	ANK_REP_REGION domain-containing protein.	0.419
nfya	LOC110971610	ENSAPOP00000001325	ENSAPOP00000000783	Nuclear transcription factor Y, alpha, like.	Signal transducer and activator of transcription.	0.546