CIITA protein (Acanthochromis polyacanthus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CIITA

Class II major histocompatibility complex transactivator. (990 aa)

Predicted Functional Partners:

rfx5

0.984

rfxank

0.935

LOC110946864

0.935

rfxap

0.919

nfya

0.873

nfyb

0.853

LOC110961881

0.839

NFYC

0.839

LOC110968507

0.839

LOC110946580

0.823

Your Current Organism:

Acanthochromis polyacanthus

NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIITA	LOC110946580	ENSAPOP00000002686	ENSAPOP00000022503	Class II major histocompatibility complex transactivator.	CCAAT enhancer binding protein beta.	0.823
CIITA	LOC110946864	ENSAPOP00000002686	ENSAPOP00000011468	Class II major histocompatibility complex transactivator.	ANK_REP_REGION domain-containing protein.	0.935
CIITA	LOC110961881	ENSAPOP00000002686	ENSAPOP00000017749	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y, gamma.	0.839
CIITA	LOC110968507	ENSAPOP00000002686	ENSAPOP00000030752	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y subunit gamma-like.	0.839
CIITA	NFYC	ENSAPOP00000002686	ENSAPOP00000028012	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y subunit gamma.	0.839
CIITA	nfya	ENSAPOP00000002686	ENSAPOP00000001325	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y, alpha, like.	0.873
CIITA	nfyb	ENSAPOP00000002686	ENSAPOP00000027997	Class II major histocompatibility complex transactivator.	Nuclear transcription factor Y, beta a.	0.853
CIITA	rfx5	ENSAPOP00000002686	ENSAPOP00000012617	Class II major histocompatibility complex transactivator.	Regulatory factor X, 5.	0.984
CIITA	rfxank	ENSAPOP00000002686	ENSAPOP00000002049	Class II major histocompatibility complex transactivator.	Regulatory factor X-associated ankyrin-containing protein.	0.935
CIITA	rfxap	ENSAPOP00000002686	ENSAPOP00000034766	Class II major histocompatibility complex transactivator.	Regulatory factor X-associated protein.	0.919
LOC110946580	CIITA	ENSAPOP00000022503	ENSAPOP00000002686	CCAAT enhancer binding protein beta.	Class II major histocompatibility complex transactivator.	0.823
LOC110946864	CIITA	ENSAPOP00000011468	ENSAPOP00000002686	ANK_REP_REGION domain-containing protein.	Class II major histocompatibility complex transactivator.	0.935
LOC110946864	rfx5	ENSAPOP00000011468	ENSAPOP00000012617	ANK_REP_REGION domain-containing protein.	Regulatory factor X, 5.	0.991
LOC110946864	rfxap	ENSAPOP00000011468	ENSAPOP00000034766	ANK_REP_REGION domain-containing protein.	Regulatory factor X-associated protein.	0.966
LOC110961881	CIITA	ENSAPOP00000017749	ENSAPOP00000002686	Nuclear transcription factor Y, gamma.	Class II major histocompatibility complex transactivator.	0.839
LOC110961881	nfya	ENSAPOP00000017749	ENSAPOP00000001325	Nuclear transcription factor Y, gamma.	Nuclear transcription factor Y, alpha, like.	0.988
LOC110961881	nfyb	ENSAPOP00000017749	ENSAPOP00000027997	Nuclear transcription factor Y, gamma.	Nuclear transcription factor Y, beta a.	0.989
LOC110968507	CIITA	ENSAPOP00000030752	ENSAPOP00000002686	Nuclear transcription factor Y subunit gamma-like.	Class II major histocompatibility complex transactivator.	0.839
LOC110968507	nfya	ENSAPOP00000030752	ENSAPOP00000001325	Nuclear transcription factor Y subunit gamma-like.	Nuclear transcription factor Y, alpha, like.	0.988
LOC110968507	nfyb	ENSAPOP00000030752	ENSAPOP00000027997	Nuclear transcription factor Y subunit gamma-like.	Nuclear transcription factor Y, beta a.	0.989