Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
vps39VPS39 subunit of HOPS complex. (876 aa)    
Predicted Functional Partners:
vps11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
   
 0.999
vps41
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
 0.999
vps33a
VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.999
vps18
VPS18 core subunit of CORVET and HOPS complexes.
   
 0.999
vps16
Vacuolar protein sorting 16 homolog.
   
 0.999
vps33b
VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family.
   
 0.992
stx17
Syntaxin 17; Belongs to the syntaxin family.
   
 
 0.991
vps8
VPS8 subunit of CORVET complex.
   
 0.985
plekhm1
Pleckstrin homology domain containing, family M (with RUN domain) member 1.
    
 
 0.970
LOC110955289
RAB7a, member RAS oncogene family.
    
 0.969
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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