Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dclk1Doublecortin-like kinase 1a. (723 aa)    
Predicted Functional Partners:
dcx
Uncharacterized protein.
   
 
 0.941
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
    
 0.846
pla2g4a
Phospholipase A2.
    
 0.795
pot1
POT1PC domain-containing protein.
    
 
 0.768
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
    
 0.690
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.690
nme9
NME/NM23 family member 8; Belongs to the NDK family.
    
 
 0.683
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.666
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
  0.658
tonsl
Tonsoku-like, DNA repair protein.
    
  0.654
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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