Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110955105Cyclin-dependent kinase-like 5. (1150 aa)    
Predicted Functional Partners:
mecp2
Methyl CpG binding protein 2.
    
 
 0.795
fmr1
Fragile X mental retardation 1.
    
 
 0.655
RAI2
Retinoic acid induced 2.
      
 0.540
arx
Aristaless related homeobox a.
      
 0.528
prune1
Prune exopolyphosphatase.
      
 0.495
pcdh19
Protocadherin 19.
      
 0.491
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
      
 0.476
stxbp1
Syntaxin binding protein 1a; Belongs to the STXBP/unc-18/SEC1 family.
      
 0.468
LOC110954531
Vav 3 guanine nucleotide exchange factor b.
      
 0.465
ntng1
Netrin g1a.
      
 0.465
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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