| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC110953042 | LOC110962689 | ENSAPOP00000020671 | ENSAPOP00000027715 | Mothers against decapentaplegic homolog. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.620 |
| LOC110953042 | LOC110964673 | ENSAPOP00000020671 | ENSAPOP00000005293 | Mothers against decapentaplegic homolog. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.789 |
| LOC110953042 | SMAD4 | ENSAPOP00000020671 | ENSAPOP00000008331 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.939 |
| LOC110953042 | cdk9 | ENSAPOP00000020671 | ENSAPOP00000010283 | Mothers against decapentaplegic homolog. | Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. | 0.653 |
| LOC110953042 | trim33 | ENSAPOP00000020671 | ENSAPOP00000003045 | Mothers against decapentaplegic homolog. | Tripartite motif containing 33. | 0.852 |
| LOC110953042 | ube2i | ENSAPOP00000020671 | ENSAPOP00000032460 | Mothers against decapentaplegic homolog. | Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. | 0.789 |
| LOC110962689 | LOC110953042 | ENSAPOP00000027715 | ENSAPOP00000020671 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Mothers against decapentaplegic homolog. | 0.620 |
| LOC110962689 | LOC110964673 | ENSAPOP00000027715 | ENSAPOP00000005293 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.947 |
| LOC110962689 | LOC110970376 | ENSAPOP00000027715 | ENSAPOP00000017046 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | SET domain-containing protein. | 0.614 |
| LOC110962689 | SMAD4 | ENSAPOP00000027715 | ENSAPOP00000008331 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Mothers against decapentaplegic homolog. | 0.620 |
| LOC110962689 | cdk9 | ENSAPOP00000027715 | ENSAPOP00000010283 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. | 0.947 |
| LOC110962689 | kdm1a | ENSAPOP00000027715 | ENSAPOP00000011557 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.985 |
| LOC110962689 | setdb1 | ENSAPOP00000027715 | ENSAPOP00000013441 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | SET domain bifurcated histone lysine methyltransferase 1b. | 0.614 |
| LOC110962689 | trim33 | ENSAPOP00000027715 | ENSAPOP00000003045 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Tripartite motif containing 33. | 0.865 |
| LOC110962689 | ube2i | ENSAPOP00000027715 | ENSAPOP00000032460 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. | 0.947 |
| LOC110964673 | LOC110953042 | ENSAPOP00000005293 | ENSAPOP00000020671 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Mothers against decapentaplegic homolog. | 0.789 |
| LOC110964673 | LOC110962689 | ENSAPOP00000005293 | ENSAPOP00000027715 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.947 |
| LOC110964673 | SMAD4 | ENSAPOP00000005293 | ENSAPOP00000008331 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Mothers against decapentaplegic homolog. | 0.789 |
| LOC110964673 | trim33 | ENSAPOP00000005293 | ENSAPOP00000003045 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Tripartite motif containing 33. | 0.870 |
| LOC110964673 | ube2i | ENSAPOP00000005293 | ENSAPOP00000032460 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. | 0.873 |