Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)    
Predicted Functional Partners:
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
    
 0.973
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
    
 0.973
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.967
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.967
LOC110964706
Cyclin D2, b; Belongs to the cyclin family.
    
 0.906
ccnd1
Cyclin D1; Belongs to the cyclin family.
    
 0.906
LOC110948419
Cyclin D2, a; Belongs to the cyclin family.
    
 0.906
LOC110957225
Cyclin D3; Belongs to the cyclin family.
    
 0.897
LOC110957520
Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily.
    
 0.889
LOC110951449
Cyclin Dx; Belongs to the cyclin family.
    
  0.885
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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