Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
htra1HtrA serine peptidase 1b. (476 aa)    
Predicted Functional Partners:
xiap
X-linked inhibitor of apoptosis.
    
 0.962
pink1
PTEN induced kinase 1.
    
 0.948
LOC110949810
RING-type domain-containing protein.
    
 0.895
LOC110965343
Baculoviral IAP repeat containing 2.
    
 0.895
LOC110953547
Baculoviral IAP repeat containing 5a.
    
 0.871
LOC110954627
Baculoviral IAP repeat containing 5b.
    
 0.871
ENSAPOP00000007183
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.856
birc6
Baculoviral IAP repeat containing 6.
    
 0.856
LOC110955776
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 0.793
LOC110962194
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 0.793
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (14%) [HD]