Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC110966501RasGEF domain family, member 1Bb. (591 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
     
 0.707
sos1
Son of sevenless homolog 1 (Drosophila).
    
 0.652
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.652
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 
 0.584
ccnk
Cyclin K; Belongs to the cyclin family.
     
  0.570
CSDE1
Cold shock domain containing E1, RNA-binding.
    
  0.526
hras
HRas proto-oncogene, GTPase a.
    
  0.526
LOC110960299
Zgc:55558.
    
  0.526
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
    
  0.526
LOC110953021
V-ral simian leukemia viral oncogene homolog Ba (ras related).
    
 0.525
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.